Upstream Bio, Inc. (UPB) — Financial statements
Income statement, balance sheet, and cash flow for Upstream Bio, Inc. — annual and quarterly history with growth and margin analysis.
| Metric (USD Millions) | 2025 | 2024 | 2023 | 2022 | |
|---|---|---|---|---|---|
| Revenue & Gross Profit | |||||
| Revenue | 3↑20.4% | 2↓0.4% | 2↑96.4% | 1 | |
| Cost of Revenue | 0.00 | 0.00 | 0.00 | 0.00 | |
| Gross Profit | 3↑20.4% | 2↓0.4% | 2↑96.4% | 1 | |
| Operating Expenses | |||||
| R&D Expenses | 137↑117.3% | 63↑98.0% | 32↑70.4% | 19 | |
| General & Administrative Expenses | 26↑53.8% | 17↑60.5% | 11↑65.5% | 6 | |
| Selling & Marketing Expenses | 0.00 | 0.00 | 0.00 | 0.00 | |
| SG&A Expenses | 26↑53.8% | 17↑60.5% | 11↑65.5% | 6 | |
| Other Expenses | 0.00 | 0.00 | 0.00 | 0.00 | |
| Operating Expenses | 163↑103.7% | 80↑88.6% | 42↑69.2% | 25 | |
| Total Costs & Expenses | 163↑103.7% | 80↑88.6% | 42↑69.2% | 25 | |
| Operating Results | |||||
| Operating Income | -160↓106.2% | -78↓93.9% | -40↓67.8% | -24 | |
| Depreciation & Amortization | 0.19↑111.2% | 0.09↑48.3% | 0.06↑757.1% | 0.01 | |
| EBITDA | -160↓106.2% | -78↓93.9% | -40↓67.6% | -24 | |
| EBIT | -160↓106.2% | -78↓93.9% | -40↓67.8% | -24 | |
| Interest & Other Income | |||||
| Net Interest Income | 17↑39.7% | 12↑191.1% | 4↑1931.7% | 0.21 | |
| Interest Income | 17↑39.7% | 12↑191.1% | 4↑1931.7% | 0.21 | |
| Interest Expense | 0.00 | 0.00 | 0.00 | 0.00 | |
| Non-Operating Income | 0.00 | 0.00 | 0.00 | 0.00 | |
| Other Income / Expenses | 17↑13.1% | 15↓23.6% | 20↑47648.8% | 0.04 | |
| Income Before Tax | -143↓128.4% | -63↓205.8% | -21↑14.0% | -24 | |
| Income Tax Expense | 0.00 | 0.00 | 0.00 | 0.00 | |
| Net Income & EPS | |||||
| Net Income from Continuing Operations | -143↓128.4% | -63↓205.8% | -21↑14.0% | -24 | |
| Net Income from Discontinued Operations | 0.00 | 0.00 | 0.00 | 0.00 | |
| Net Income | -143↓128.4% | -63↓205.8% | -21↑14.0% | -24 | |
| Bottom-Line Net Income | -143↓87.8% | -76↓99.7% | -38↓60.3% | -24 | |
| EPS (Basic) | -2.66↓78.5% | -1.49↓41.9% | -1.05↓59.1% | -0.66 | |
| EPS (Diluted) | -2.66↓78.5% | -1.49↓41.9% | -1.05↓59.1% | -0.66 | |
| Weighted Average Shares | 54↑4.9% | 51↑41.3% | 36↑0.0% | 36 | |
| Weighted Average Diluted Shares | 54↑4.9% | 51↑41.3% | 36↑0.0% | 36 | |
* All figures in Millions of USD, except per share data. Growth rates calculated Year-over-Year (YoY). Data source: SEC Filings.